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Search Results for " cell division "

77

抑制剂 & 化合物

17

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8513	Spastazoline	Others	Others
	Spastazoline 是spastin(一种微管切断AAA 蛋白) 的选择性抑制剂，对人 spastin 的IC50值为 99 nM。它不能影响重组人 VPS4 的 ATPase 活性。
T6393	ARQ 621	Kinesin	Cytoskeletal Signaling
	ARQ 621 是一种变构和选择性 Eg5 有丝分裂运动蛋白抑制剂，具有抗肿瘤活性。
T12642L	Simurosertib TAK-931	CDK	Cell Cycle/Checkpoint
	Simurosertib (TAK-931) 是一种选择性和 ATP 竞争性细胞分裂周期 7 激酶抑制剂，具有抗癌活性，IC50值小于 0.3 nM。
T21678	3MB-PP1	PLK	Cell Cycle/Checkpoint
	3MB-PP1是嘌呤类似物，是一种 Polo 样激酶 1 (Plk1) 抑制剂。在表达类似物敏感的 Plk1 等位基因的细胞中，3MB-PP1 通过靶向 Plk1 阻断有丝分裂进程和细胞分裂。3MB-PP1 特异性抑制类似物敏感的 Ssn3 (Cdk8)。3MB-PP1 抑制 Leu93 突变 Zipper-interacting protein kinase(Leu93-ZIPK)，IC50为2 μM。3MB-PP1 可用于细胞分裂和白色念珠菌 (Candida albicans) 菌丝形成的研究。
T21970	ML-097	GTPase	GPCR/G Protein
	ML-097 是 Ras 相关 GTP 酶的泛激活剂。
T0849	Pyrimethamine Pirimecidan,RP 4753,Pirimetamin,乙胺嘧啶	DHFR; Antifolate; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Pyrimethamine (Pirimecidan) 是一种二氢叶酸还原酶的竞争性抑制剂，用作抗疟药。
T22991	ML-099	Rho; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	ML-099 是广谱的 Ras 相关GTPases 激活剂，对Rac1、cell division cycle 42、Ras、Rab7和Rab-2A 均有激活作用。
T8586	cicloprofen	Others	Others
	cicloprofen 是细胞分裂周期 7 相关蛋白激酶（人）抑制剂。
T15141	DM4 Ravtansine,美登素 DM4	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	DM4 (Ravtansine)可用于制备抗体药物偶联物，是抗微管蛋白剂。它抑制细胞分裂。
T12642	(R)-Simurosertib (R)-TAK-931	CDK	Cell Cycle/Checkpoint
	(R)-Simurosertib ((R)-TAK-931) 是具有 ATP 竞争作用的细胞分裂周期 7 (CDC7) 激酶的抑制剂。
T3256	MMAF 一甲基澳瑞他汀 F,MonoMethyl auristatin F	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	MMAF (MonoMethyl auristatin F) 是一种抗有丝分裂剂，通过阻断微管蛋白的聚合来抑制细胞分裂，用作抗肿瘤药物和抗体偶联药物的细胞毒性成分。
T3352	XL413	cholecystokinin; Casein Kinase; Pim; CDK	Cell Cycle/Checkpoint; Chromatin/Epigenetic; GPCR/G Protein; JAK/STAT signaling; Metabolism; Stem Cells
	XL413 是一种口服生物可利用的细胞分裂周期 7 同源物 (CDC7) 激酶抑制剂，具有潜在的抗肿瘤活性，IC50值为 3.4 nM。它对 pMCM 的 EC50值为 118 nM，对 CK2 和 PIM1 的 IC50值分别为 215 和 42 nM。
T6897	Monomethyl auristatin E 一甲基澳瑞他汀E,Vedotin,MMAE	Apoptosis; Microtubule Associated	Apoptosis; Cytoskeletal Signaling
	Monomethyl auristatin E (MMAE) 是海兔毒素 10 的合成衍生物，是一种抗有丝分裂剂，通过阻断微管蛋白的聚合来抑制细胞分裂，并且还具有抑制抗体-药物偶联物的活性。
T6437	Cefoperazone 头孢哌酮,Cefob,Medocef	Antibacterial; Antibiotic	Microbiology/Virology
	Cefoperazone (Medocef) 是一种半合成的头孢菌素，有抗菌活性。
T1060	Flumequine Flumigal,氟甲喹,R-802	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Flumequine (R-802) 是一种喹诺酮类抗生素，对革兰氏阳性菌和革兰氏阴性菌均有效。它是拓扑异构酶 II 抑制剂，抑制细胞分裂，IC50值为 15 μM (3.92 μg/mL)。
T14348	Auristatin E	Microtubule Associated	Cytoskeletal Signaling
	Auristatin E 通过阻断微管蛋白的聚合来抑制细胞分裂。它是一种细胞毒性微管蛋白修饰剂，具有强效和选择性抗肿瘤活性。它是一种 MMAE 类似物，是抗体-药物偶联物中的细胞毒素。
T11929	M2N12	Phosphatase	Metabolism
	M2N12 是一种高度选择性的细胞分裂周期蛋白磷酸酶 25C 抑制剂，IC50值为 0.09 μM。它还抑制 Cdc25A 和 Cdc25B 的活性，IC50值分别为 0.53 μM 和 1.39 μM。它具有抗肿瘤活性，可研究癌症。
T1228	Cefonicid sodium Monocid sodium,头孢尼西钠,Cefonicid disodium salt	Antibacterial; Antibiotic	Microbiology/Virology
	Cefonicid sodium (Monocid sodium) 是一种广谱头孢类抗生素, 能抑制细菌细胞壁的形成。
T2511	Plinabulin 普那布林,NPI-2358	Microtubule Associated	Cytoskeletal Signaling
	Plinabulin (NPI-2358) 是一种抗微管蛋白解聚肿瘤细胞的血管破坏剂，选择性地靶向并结合到微管蛋白的秋水仙碱结合位点，从而中断微管动力学的平衡。它对人肿瘤细胞系具有抑制作用，对 HT-29 细胞系的IC50值为 9.8 nM。
T1213	Piperacillin sodium 哌拉西林钠,Sodium piperacillin,CL227193,Piperacillin sodium salt	Antibacterial; Antibiotic	Microbiology/Virology
	Piperacillin sodium salt(CL227193) )是一种β-内酰胺类广谱抗生素。
T4433	6-CFDA N-succinimidyl ester Carboxyfluorescein diacetate succinimidyl	Others	Others
	6-CFDA N-succinimidyl ester (Carboxyfluorescein diacetate succinimidyl) 能够自发且不可逆地与游离胺结合。在流式细胞术实验中用于追踪哺乳动物细胞和细菌的细胞分裂。与多种细胞透化剂结合使用，作为一种有效的、非破坏性的荧光染料，可快速检测细菌细胞。
T3661	Citarinostat ACY241,HDAC-IN-2	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Citarinostat (ACY241) 是一种强效、选择性和口服组蛋白脱乙酰酶 (HDAC) 抑制剂，具有抗肿瘤活性，对 HDAC1、HDAC2、HDAC3、HDAC6 和 HDAC8 的 IC50分别为 35、45、46、2.6 和 137 nM。
T1122	Cephalothin sodium 头孢噻吩钠,Cefalotin sodium,Cephalothin,Cefalotin	Antibacterial; Antibiotic	Microbiology/Virology
	Cephalothin sodium (Cefalotin) 是一种头孢类抗生素, 具有广泛的抗菌活性，抑制革兰氏阳性和阴性菌。
T10735	CDK4/6/1 Inhibitor Crozbaciclib	CDK	Cell Cycle/Checkpoint
	CDK4/6/1 Inhibitor (Crozbaciclib) 是一种 CDK4/6 抑制剂 (IC50s: 3 and 1 nM). CDK4/6抑制剂是一类用于治疗一些类型的激素受体阳性、her2阴性乳腺癌的化合物，可阻断了乳腺癌细胞分裂和繁殖的过程。
T1600	Doxifluridine Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine,去氧氟尿苷	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Doxifluridine (AMC 0101) 是一种胸苷磷酸化酶活化剂，对 PC9-DPE2细胞的 IC50为0.62 μM。它是具有抗肿瘤活性的抗肿瘤剂 5-fluorouracil (5-FU) 的氟嘧啶衍生物和口服前药。
T67509	Cholesteryl Hemisuccinate Cholesterol hydrogen succinate	Apoptosis; DNA/RNA Synthesis; Topoisomerase	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) 是一种经常使用在极性溶液中具有高溶解度的胆固醇类似物，具有保肝、抗癌和抑制肿瘤生长的作用。Cholesteryl Hemisuccinate 抑制对乙酰氨基酚的肝毒性，并防止 AAP 诱导的肝细胞凋亡和坏死。Cholesteryl Hemisuccinate 抑制 DNA 聚合酶和 DNA 拓扑异构酶，从而抑制 DNA 复制和修复以及细胞分裂。
T3615	Evofosfamide 艾伏磷酰胺,TH-302	Apoptosis; Others	Apoptosis; Others
	Evofosfamide (TH-302) 是一种缺氧激活前药，在缺氧 (N2) 和常氧 (21% O2) 环境下，IC50分别为 10 μM 和 1000 μM。
T1408	Capecitabine Xeloda,卡培他滨,Capecitibine,Capiibine,RO 09-1978	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Capecitabine (Capecitibine) 是一种可口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。
T25529	IMM-01	GTPase	GPCR/G Protein
	IMM-01 是一类新型的哺乳动物透明 (mDia) 相关形式的小分子激动剂，其作用于 Rho GTPase 下游以组装肌动蛋白丝，并与微丝组织在迁移和不对称分裂过程中建立和维持细胞极性. GTP 结合的 Rho 通过破坏 DID 和 DAD 自动调节结构域之间的相互作用来激活 mDia 家族成员，从而释放 FH2 结构域以调节肌动蛋白和微管动力学。
T40443	JAK2-IN-6 JAK2-IN-6	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	JAK2-IN-6是一种有效的、有选择性的 JAK2抑制剂(ic50为22.86 μg/mL),是一种多取代氨基噻唑衍生物。JAK2-IN-6抑制 JAK2酶的活性，通过干扰与 JAK2相关的信号通路，从而对 JAK2失调的特定疾病产生治疗作用，对 JAK1和JAK3不显示出活性。JAK2是一种参与调节细胞生长和分裂的信号通路的蛋白质。JAK2的异常激活与多种疾病有关，包括某些类型的癌症和炎症性疾病。JAK2-IN-6对癌细胞具有抗增殖活性。
T24126	Gyramide A Gyramide-A
	Gyramide A is an inhibitor of bacterial DNA gyrase. It shows antimicrobial activity and inhibits bacterial cell division.
T19830	Dicapthon AC4124,AC 4124,Captex,ENT-17035,ENT 17035,AC-4124
	Dicapthon is an insecticide. Dicapthon increases the occurrence of abnormal cell frequency, decreases the mitotic index, and decreases the nuclear division index.
T34924	Triadimenol Spinnaker,UK199,Baytan,UK 199,UK-199
	Triadimenol is a systemic fungicide with a broad spectrum. It inhibits the ergosterol - and gibberellin - biosynthesis, and thus the rate of cell division.
T31838	Folic acid, methyl- x-Methylfolic acid,x-Methyl folic acid,x-Methylpteroylglutamic acid
	Folic acid, methyl- is a nutrient that belongs to the vitamin B family. Folate is significant for the easy conversion of carbohydrates into glucose and is essential in red blood cell formation, cell division, detoxification, and the production of some neu
T23578	(S)-Gyramide A (S)-Gyramide-A,(S)-534F6,(S)534F6,(S) 534F6
	(S)-Gyramide A is a bacterial DNA gyrase inhibitor that acts by exhibiting antimicrobial activity and inhibiting bacterial cell division.
T38428	Alisertib sodium MLN 8237 sodium
	Alisertib sodium (MLN 8237) is a potent and specific inhibitor (IC50 = 1.2 nM) of Aurora A kinase, an enzyme involved in cell division. By binding to Aurora A kinase, Alisertib sodium disrupts the formation of the mitotic spindle and causes abnormal cell division. At the molecular level, it acts on the AKT/mTOR/AMPK/p38 pathway, leading to the induction of apoptosis and autophagy in leukemic cells. This compound exhibits significant antitumor activity.
T70958	Dov-Val-Dil-OH TFA
	Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the polymerisation of tubulin.
T40782	Metazachlor
	Metazachlor, a member of the chloroacetamide class of herbicides, acts as a long chain fatty acid synthesis inhibitor. It exerts an influence on cell division and tissue differentiation in germinating and emerging weed species.
T72934	Epothilone E 埃博霉素E
	Epothilone E，作为Epothilone的衍生化合物，通过抑制微管蛋白功能来阻碍细胞分裂，从而展现出抗肿瘤活性。
T36106	Coumermycin A1
	Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Coumermycin A1-induced-JAK2 signal activation increases the mRNA level of SCOS2, but reducea leptin receptor mRNA level[1]. [1]. Tiantian Zhang, et al. SOCS2 Inhibits Mitochondrial Fatty Acid Oxidation via Suppressing LepR/JAK2/AMPK Signaling Pathway in Mouse Adipocytes. Research Article.
T21298	SNS-314 SNS-314 free base,SNS314,SNS 314
	SNS-314, a synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity, selectively binds and inhibits AKs A and B, resulting in the inhibition of cell division and proliferation in tumor cells that overexpress AKs.
T25043	Alestramustine
	Alestramustine is a cytostatic antineoplastic agent. The drug, via its active metabolites, binds to microtubule-associated proteins and β-tubulin and interferes with microtubule function, thereby suppressing cell division. Due to its estrogen moiety, Ales
T11042	Dihydrocytochalasin B	Others	Others
	Dihydrocytochalasin B (H2CB) is a cell division inhibitor that changes the morphology of cells, similar to cytochalasin B. Does not inhibit glucose transport. Dihydrocytochalasin B (H2CB) disrupts the structure of actin and inhibits the ability of growth
T36801	Binucleine 2
	Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-dependent manner, with minimal inhibition of human or X. laevis Aurora B kinases at concentrations up to 100 μM. Binucleine 2 induces mitotic and cytokinesis defects in Drosophila Kc167 cells. It prevents Drosophila S2 cells from assembling a contractile ring during cell division ...
T70942	AM-8508
	AM-8508 is a potent and selective PI3Kδ inhibitor. AM-8508 showed good cellular potency (in vitro pAKT IC50 = 4.6 nM ). AM-8505 xhibited excellent HWB potency (HWB (pAKT) IC50 = 2.7 nM). AM-8508 inhibit KLH-specific antibodies in animal models, signifying its potential for the treatment of human inflammatory diseases. PI3Kα and PI3Kβ are ubiquitously expressed and play a role in cell growth, division, and survival.
TP2192	Cdk2/Cyclin Inhibitory Peptide I	Others	Others
	Cyclin-dependent kinase 2 also known as cell division protein kinase 2. The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases. This protein kinase is highly similar to the gene products of S. cerevis
T69305	Milataxel
	Milataxel is an orally bioavailable taxane with potential antineoplastic activity. Upon oral administration, milataxel and its major active metabolite M-10 bind to and stabilize tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, milataxel appears to be a poor substrate for the multidrug resistance (MDR) membrane-associated P-glycoprotein (P-gp) ...
T70808	Cabazitaxel-d6
	Cabazitaxel-d6 is a deuterium labeled cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane-associated, multidrug resistance...
T70748	Bisthianostat
	Bisthianostat, also known as CF367 or CF367;-C, is a novel Orally Efficacious Pan-HDAC Inhibitor. Bisthianostat selectively binds to and inhibits HDACs, which inhibits deacetylation of histone proteins and leads to the accumulation of highly acetylated histones. This may result in an induction of chromatin remodeling, the inhibition of tumor oncogene transcription, and the selective transcription of tumor suppressor genes. This prevents cell division, induces cell cycle arrest and apoptosis. Thi...
T74555	EDA-DA
	EDA-DA 是一种 N 末端标记的二肽探针，可用于标记细菌的肽聚糖 (PG)。肽聚糖 (PG) 是绝大多数细菌细胞壁中的一种基本结构，对于分裂和维持细胞形状和静水压力至关重要。

化合物

Cat.No: T8513

Target: Others

Cat.No: T6393

Target: Kinesin

Cat.No: T12642L

Synonym: TAK-931

Target: CDK

Cat.No: T21678

Target: PLK

Cat.No: T21970

Target: GTPase

Cat.No: T0849

Synonym: Pirimecidan,RP 4753,Pirimetamin,乙胺嘧啶

Target: DHFR, Antifolate, Parasite

Cat.No: T22991

Target: Rho, Ras

Cat.No: T8586

Target: Others

Cat.No: T15141

Synonym: Ravtansine,美登素 DM4

Target: Others, Microtubule Associated

(R)-Simurosertib

Cat.No: T12642

Synonym: (R)-TAK-931

Target: CDK

Cat.No: T3256

Synonym: 一甲基澳瑞他汀 F,MonoMethyl auristatin F

Target: Others, Microtubule Associated

Cat.No: T3352

Target: cholecystokinin, Casein Kinase, Pim, CDK

Monomethyl auristatin E

Cat.No: T6897

Synonym: 一甲基澳瑞他汀E,Vedotin,MMAE

Target: Apoptosis, Microtubule Associated

Cat.No: T6437

Synonym: 头孢哌酮,Cefob,Medocef

Target: Antibacterial, Antibiotic

Cat.No: T1060

Synonym: Flumigal,氟甲喹,R-802

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T14348

Target: Microtubule Associated

Cat.No: T11929

Target: Phosphatase

Cefonicid sodium

Cat.No: T1228

Synonym: Monocid sodium,头孢尼西钠,Cefonicid disodium salt

Target: Antibacterial, Antibiotic

Cat.No: T2511

Synonym: 普那布林,NPI-2358

Target: Microtubule Associated

Piperacillin sodium

Cat.No: T1213

Synonym: 哌拉西林钠,Sodium piperacillin,CL227193,Piperacillin sodium salt

Target: Antibacterial, Antibiotic

6-CFDA N-succinimidyl ester

Cat.No: T4433

Synonym: Carboxyfluorescein diacetate succinimidyl

Target: Others

Cat.No: T3661

Synonym: ACY241,HDAC-IN-2

Target: HDAC

Cephalothin sodium

Cat.No: T1122

Synonym: 头孢噻吩钠,Cefalotin sodium,Cephalothin,Cefalotin

Target: Antibacterial, Antibiotic

CDK4/6/1 Inhibitor

Cat.No: T10735

Synonym: Crozbaciclib

Target: CDK

Cat.No: T1600

Synonym: Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine,去氧氟尿苷

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cholesteryl Hemisuccinate

Cat.No: T67509

Synonym: Cholesterol hydrogen succinate

Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase

Cat.No: T3615

Synonym: 艾伏磷酰胺,TH-302

Target: Apoptosis, Others

Cat.No: T1408

Synonym: Xeloda,卡培他滨,Capecitibine,Capiibine,RO 09-1978

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T25529

Target: GTPase

Cat.No: T40443

Synonym: JAK2-IN-6

Target: JAK

Cat.No: T24126

Synonym: Gyramide-A

Cat.No: T19830

Synonym: AC4124,AC 4124,Captex,ENT-17035,ENT 17035,AC-4124

Cat.No: T34924

Synonym: Spinnaker,UK199,Baytan,UK 199,UK-199

Folic acid, methyl-

Cat.No: T31838

Synonym: x-Methylfolic acid,x-Methyl folic acid,x-Methylpteroylglutamic acid

Cat.No: T23578

Synonym: (S)-Gyramide-A,(S)-534F6,(S)534F6,(S) 534F6

Alisertib sodium

Cat.No: T38428

Synonym: MLN 8237 sodium

Dov-Val-Dil-OH TFA

Cat.No: T70958

Cat.No: T40782

Cat.No: T72934

Synonym: 埃博霉素E

Cat.No: T36106

Cat.No: T21298

Synonym: SNS-314 free base,SNS314,SNS 314

Cat.No: T25043

Dihydrocytochalasin B

Cat.No: T11042

Target: Others

Cat.No: T36801

Cat.No: T70942

Cdk2/Cyclin Inhibitory Peptide I

Cat.No: TP2192

Target: Others

Cat.No: T69305

Cat.No: T70808

Cat.No: T70748

Cat.No: T74555

Cat. No.	Product Name	Target	Signaling Pathways
T13818	Phytohemagglutinin PHA-M,植物血球凝集素,PHA,植物血凝素	Apoptosis	Apoptosis
	Phytohemagglutinin (PHA-M) 是一种普通豆菜豆的主要种子凝集素，聚集在子叶的薄壁细胞中。它是一种 T 细胞激活剂，能够刺激人单核白细胞，可诱导 ChAT mRNA 表达，增强 ACh 合成。
T8211	(±)-Decursinol 紫花前胡醇,3',4'-dihydro-3'-hydroxy-Xanthyletin	Others; Antibacterial	Microbiology/Virology; Others
	(±)-Decursinol (3',4'-dihydro-3'-hydroxy-Xanthyletin) 是来自当归的一种 FtsZ 抑制剂，抑制 B. anthracis 的 FtsZ 聚合，IC50为 102 μM。
T2942	Psoralen Ficusin,Furocoumarin,补骨脂素,psoralene	Apoptosis; Influenza Virus; HIV Protease; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Psoralen (Ficusin) 是从补骨脂种子中提取的一种香豆素。它具有如抗癌、抗氧化、抗抑郁、抗癌、抗菌、抗病毒等多种生物学特性。
T14304	Aphidicolin	Others	Others
	Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus[2]. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering with the activity of DNA
T3151	Brassinolide Brassin lactone,24-Epibrassinolide,芸苔素内酯	Apoptosis; Others	Apoptosis; Others
	Brassinolide (Brassin lactone) 是一种植物生长调节剂，可调节植物细胞伸长。
TMS2181	trans-Zeatin (E)-Zeatin,玉米素	ERK; MEK; Endogenous Metabolite	MAPK; Metabolism
	trans-Zeatin ((E)-Zeatin) 是植物细胞分裂素，可抑制紫外线诱导的MEK/ERK 的活化，在细胞生长、分化和分裂中起着重要的作用。
TMS2182	trans-Zeatinriboside Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside,玉米素核苷	Others	Others
	trans-Zeatinriboside (Ribosylzeatin) 是一种细胞分裂素前体，是木质素导管中主要的长距离信号形式，能够调节叶片大小和分生组织活性相关形状。
T7132	(Rac)-Brassinazole BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑	P450	Metabolism
	(Rac)-Brassinazole 是三唑型化合物，是油菜素甾醇 (BR) 生物合成抑制剂。它能够增强 CYP90B 在 BR 生物合成中的抑制作用。
T1004	6-Benzylaminopurine 6-苄氨基嘌呤,6-BAP,N6-Benzyladenine,BA,Benzyladenine	Others	Others
	6-Benzylaminopurine (6-BAP) 是一种细胞分裂素，能够通过刺激细胞分裂引起植物生长和发育，抑制呼吸激酶，从而延长绿色蔬菜的保鲜。
TMS2179	Zeatin 玉米素	Others	Others
	Zeatin 是一种来源于腺嘌呤的细胞分裂素。Zeatin 是在玉米属的未成熟玉米粒中发现的。它促进侧芽的生长，当喷洒在分生组织上时会刺激细胞分裂，从而产生更浓密的植物。
T5088	3-Indoleacetic acid sodium Indole-3-Acetic Acid sodium salt,Sodium 2-(1H-indol-3-yl)acetate,IAA sodium salt,吲哚乙酸钠,Heteroauxin sodium salt	Others; Endogenous Metabolite	Metabolism; Others
	3-Indoleacetic acid sodium (Heteroauxin sodium salt) 是一种天然存在的植物生长素类激素。能刺激细胞伸长和分裂，促进植物生长发育。然而，高浓度时，它表现出生长抑制作用，包括生长和阻止茎和根的生长。后一种效应形成了合成生长素被开发为农业除草剂和生物调节剂的基础。
TMM2618	Gibberllin A7 Gibberellin A7,Gibberllin 7,赤霉素GA7	Others	Others
	Gibberllin A7 (Gibberllin 7) 是重要的植物生长激素，可促进植物细胞生长和伸长。它可促进茎和根的快速生长，诱导有丝分裂并启动（打破休眠）并提高种子发芽率。它还参与诸如作为向地力、张力和花卉展示。Gibberellin A3(G1025, G7645) 和 A4 (G7276) 可用作植物生长培养基如 Murashige 和 Skoog 培养基的补充剂。 A3 和 A4 或 Gebberellins 组合的具体作用应在具体的植物应用中确定。
T38141	Glycerophospholipids, cephalins Phosphatidylethanolamines (egg)
	Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物，在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用，可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。
T4454	Traumatic Acid Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,愈伤酸,Trans-2-Dodecenedioic Acid	Antioxidant	oxidation-reduction
	Traumatic Acid (Dodec-2-Enedioic Acid) 是一种单不饱和二元羧酸，从菜豆中分离得到。它可减少膜磷脂的过氧化，并表现出抗氧化和对胶原生物合成的刺激作用。它可用于许多与胶原蛋白生物合成障碍和氧化应激有关的皮肤疾病的研究。
T75520	Aplyronine A
	Aplyronine A是具有特异性肌动蛋白解聚活性、抗肿瘤及促凋亡功能的化合物，适用于癌症、肌肉收缩、细胞运动和细胞分裂等研究领域。
TN4890	Rabdosin B	Others	Others
	Rabdosin B shows cytotoxic activity against three human tumour HepG2, GLC-82 and HL-60 cell lines, it induces significant DNA damage to HepG2 cells in a time- and dose-dependent manner. Rabdosin B at higher concentrations inhibits root growth by affecting
TN4249	Ilicol	Others	Others
	Pinocembrin and Ilicol inhibit root growth and show IC50 (root growth) values of 0.199, 14.68, 8.05, 7.69 mM, and 1.22, 2.90, 7.35, 8.07 mM, against P. miliaceum, A. sativa, L. sativa, and R. sativus, respectively. They reduce Allium cepa cell

天然产物

Phytohemagglutinin

Cat.No: T13818

Synonym: PHA-M,植物血球凝集素,PHA,植物血凝素

Target: Apoptosis

(±)-Decursinol

Cat.No: T8211

Synonym: 紫花前胡醇,3',4'-dihydro-3'-hydroxy-Xanthyletin

Target: Others, Antibacterial

Cat.No: T2942

Synonym: Ficusin,Furocoumarin,补骨脂素,psoralene

Target: Apoptosis, Influenza Virus, HIV Protease, DNA/RNA Synthesis

Cat.No: T14304

Target: Others

Cat.No: T3151

Synonym: Brassin lactone,24-Epibrassinolide,芸苔素内酯

Target: Apoptosis, Others

Cat.No: TMS2181

Synonym: (E)-Zeatin,玉米素

Target: ERK, MEK, Endogenous Metabolite

trans-Zeatinriboside

Cat.No: TMS2182

Synonym: Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside,玉米素核苷

Target: Others

(Rac)-Brassinazole

Cat.No: T7132

Synonym: BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑

Target: P450

6-Benzylaminopurine

Cat.No: T1004

Synonym: 6-苄氨基嘌呤,6-BAP,N6-Benzyladenine,BA,Benzyladenine

Target: Others

Cat.No: TMS2179

Synonym: 玉米素

Target: Others

3-Indoleacetic acid sodium

Cat.No: T5088

Synonym: Indole-3-Acetic Acid sodium salt,Sodium 2-(1H-indol-3-yl)acetate,IAA sodium salt,吲哚乙酸钠,Heteroauxin sodium salt

Target: Others, Endogenous Metabolite

Cat.No: TMM2618

Synonym: Gibberellin A7,Gibberllin 7,赤霉素GA7

Target: Others

Glycerophospholipids, cephalins

Cat.No: T38141

Synonym: Phosphatidylethanolamines (egg)

Cat.No: T4454

Synonym: Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,愈伤酸,Trans-2-Dodecenedioic Acid

Target: Antioxidant

Cat.No: T75520

Cat.No: TN4890

Target: Others

Cat.No: TN4249

Target: Others

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